conditions a-z
Incontinence (Bladder)
Women’s Health Program
Incontinence of bladder has several causes and patterns. Stress incontinence occurs when the bladder is stressed, such as with coughing or jumping. Urge incontinence occurs usually when the bladder spasms, due to irritability or deficiency of nutrients such as magnesium. Women usually experience more incontinence than men because of a shorter urethra and childbirth. Both men and women, as they age, experience muscle and tissue atrophy of the pelvic floor. Medical evaluation for conditions such as bladder infection, bladder polyps and other causes should be considered before embarking on any home treatments.
Fortunately, exercises to strengthen the pelvic floor, called Kegel exercises, help in the vast majority of cases. Devices previously only available at urologists offices are now available for home use that allow for more effective exercising of the pelvic muscles. One such device is the Perifit, which connects to a smart phone by bluetooth and allows for progressive strengthening.
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Dry Eye
Eye Menu
I always suspected that the pressure issues in glaucoma were secondary; as is evidenced by “normal pressure” glaucoma, where the same damage to the retina is seen. The retina is one of the most chemically-active tissues, having to concentrate light and then process it. It makes sense that it would be particularly vulnerable to different metabolic stressors. In addition, it also makes sense that since metabolic stressors can be different, the type of damage could be different. I believe this applies to glaucoma and macular degeneration. Just as with high- and low-pressure glaucoma, there is wet and dry macular degeneration. Do these labels/categories really apply or are they all variants of an underlying root cause? We could also include cataracts, where the damage from the sun affects the lens separately from the retina. There is good data on the mechanism of cataract and potential modulators/remedies.
Back to glaucoma, I’ve collected some recent articles that support this idea and suggest that one of my core nutients, niacin, may have a role in its prevention and even possible reversal.
References (start at the top)
Crosstalk Between Dysfunctional Mitochondria and Inflammation in Glaucomatous Neurodegeneration.2021
Nicking-Glaucoma-with-Nicotinamide.2017.nejm
Glaucoma as a Metabolic Optic Neuropathy–Making the Case for Nicotinamide Treatment in Glaucoma
!Bone Lead Levels and Risk of Incident Primary Open-Angle Glaucoma–The VA Normative Aging Study.2018
Diurnal and 24-h Intraocular Pressures in Glaucoma
Medical Management of Glaucoma in the 21st Century from a Canadian Perspective.2016
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Insulin
Hormones and Metabolism Program
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Tests
Blood
Radiology Non-Invasive
Stress
Invasive
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Glucagon
Hormones and Metabolism Program
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Tests
Blood
Radiology Non-Invasive
Stress
Invasive
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Incretin
Hormones and Metabolism Program
Incretin is a hormone made by the small intestines that has an effect on hunger and insulin release. Pharmaceutical analogues include ___________. They were approved in June 2021 by the FDA for use for weight managment. Whether they have to be taken long-term remains unknown.
FDA Approves New Drug Treatment for Chronic Weight Management_2021_06
The New Side of Incretin-Based Therapy in Type 2 Diabetes–Exploring Advances From EASD 2021
The New Side of Incretin-Based Therapy in Type 2 Diabetes–Exploring Advances From EASD 2021
New Insights Into the Role of Incretins in the Treatment of Diabetes.2005
Tests
Blood
Radiology Non-Invasive
Stress
Invasive
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