Ehlers-Danlos Syndrome (EDS)

Updated January 7, 2022

There are two forms of EDS, Congenital and Acquired. In both cases, the connective tissues are weak, causing a host of symptoms and signs listed below. The congenital form is a rare genetic disoreder, while the newer “acquired” form is often associated with many of the complaints of the ME/CFS and related communities.

Symptoms of EDS:

hypermobility of joints

lack of structural integrity of internal organs, including aorta, gut, etc.

hypotension, with consequent fatigue, fainting, etc., progressing to:

POTS (postural orthstatic tachycardia syndrome)

References

Ehlers–Danlos syndromes – Wikipedia

Youtube on EDS

Ehlers-Danlos syndromes- state of the art on clinical practice guidelines

Cellular and Molecular Mechanisms in the Pathogenesis of Classical, Vascular, and Hypermobile Ehlers‒Danlos Syndromes

Cardiovascular autonomic dysfunction in Ehlers-Danlos syndrome-Hypermobile type. – PubMed – NCBI

Postural tachycardia syndrome and other forms of orthostatic intolerance in Ehlers-Danlos syndrome. – PubMed – NCBI

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Hypotension

POTS