Inflammatory Bowel Disease includes Crohns Disease, Ulcerative Colitis, and other autoimmune-related bowel dysfunctions (such as with some cases of vasculitis). It does not include non-inflammatory conditions which include Irritable Bowel Syndrome (IBS) of all types or  chronic diarrhea or constipation. By virtue of their autoimmune nature, they share immune dysfunction as a part of the root-causes-complex.

IBD’s can be mild with rare episodes, or aggressive, rapidly damaging the lower (and sometimes spreading to the upper) GastroIntestinal Tract (GIT).  Older medications such as steroids (cortisone, prednisone) and others such as sulfasalazine can calm the situation down enough to enable time for the holistic approach to ramp up. Sometime the new immune-modulating drugs are necessary.  Modalities such as Low Dose Naltrexone (LDN) are being explored by mainstream medicine (such as at the U of Pittsburgh), as well as by the holistic community.

Incorporating strategies for sub-clinical yeast and parasitic infections, toxicities, biofilms, epigenetic modulation and total-body biome (ecology) can improve the rate and depth of healing.

Testing

Testing for IBD is not always yielding. Conventional medicine usually offers upper and lower endoscopy (colonoscopy), blood tests, and stool testing. Private labs offer more comprehensive gut testing such as ecological and chemical stool testing. 

Bowel Disorders Evaluation Rule-out Cascade-LabCorp 162045

References

Ulcerative Colitis by Jonathan Wright

Microbial Metabolite Regulation of Epithelial Cell-Cell Interactions and Barrier Function.2022

The Gut Microbiota Metabolite Succinate Promotes Adipose Tissue Browning in Crohn’s Disease.2022

Succinate metabolism and its regulation of host-microbe interactions.2023.r

Efficacy of a Preparation Based on Calcium Butyrate, Bifidobacterium bifidum, Bifidobacterium lactis, and Fructooligosaccharides in the Prevention of Relapse in Ulcerative Colitis–A Prospective Observational Study.2021

Diet–Microbiota Interactions in Inflammatory Bowel Disease.2021

Inflammatory Bowel Disease– A Potential Result from the Collusion between Gut Microbiota and Mucosal Immune System.2019

Controlling Gut Inflammation by Restoring Anti-Inflammatory Pathways in Inflammatory Bowel Disease.2019

Natural Products as a Source of Anti-Inflammatory Agents Associated with Inflammatory Bowel Disease

Anti-Inflammatory Effects of Fargesin on Chemically Induced Inflammatory Bowel Disease in Mice.2018

Therapeutic Potential of Amino Acids in Inflammatory Bowel Disease.2019

Inflammatory Bowel Disease Types Differ in Markers of Inflammation, Gut Barrier and in Specific Anti-Bacterial Response.2019

Sex- and Age-Related Estrogen Signaling Alteration in Inflammatory Bowel Diseases–Modulatory Role of Estrogen Receptors.2019

Selenium and Selenoproteins in Gut Inflammation—A Review.2018

Huang-Lian-Jie-Du Decoction Ameliorates Acute Ulcerative Colitis in Mice via Regulating NF-B and Nrf2 Signaling Pathways and Enhancing Intestinal Barrier Function.2019