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The immune system is like a roving brain that provides surveillance on the outside and inside of our bodies against invasion. When the immune system becomes under-reactive, we develop infections and cancer. When the immune system is over-active, we develop allergies and autoimmune disease. We can have too much (cardio-vascular disease), or too little (cancer).
While intimately connected to our hormones and metabolism, we have lots of information about different aspects of immune dysfunction: