Updated December 25, 2022

Thyroperoxidase (TPO) is an extremely important enzyme, mostly located in the thyroid gland.  Since it is intimately involved in the production of thyroid hormone, it’s dysfunction can affect every cell of the body, and it often does.  The epidemic of thyroid disease, more prevalent than diabetes, is in part due to the dysfunction of this enzyme.

In Hashimoto’s thyroiditis, the most prevalent thyroid disorder and one of the most prevalent autoimmune diseases, the body makes antibodies to TPO as well as to Thryoglobulin.

This post will collect information specific to TPO, while other posts will focus on Hashimotos, Iodine, and related topics as can be seen in the menu at the top of the page.

Thyroid Peroxidase Activity is Inhibited by Phenolic Compounds—Impact of Interaction.2019.r