Niacin & Niacinamide (B3)

Vitamins

Niacin, Vitamin B3, originally named “nicotinic acid” is a nutrient that goes back to the beginning of life. It plays a major role in genetics (via NAD, NADP and related molecules, brain function, cancer prevention, heart disease, and detoxification of fat-seeking toxins.
While it requires finesse in its management, it is a magnificent anti-aging and anti-cancer agent. The RDA of 18 mg is way too low. Hoffer took 3,000 – 4,500 mg a day of niacin, but most people struggle even with 25 to 50 mg. Separately niacinamide can be taken at 500 mg twice a day which does not have the same scope as niacin but is proven to help with skin cancer (and possibly other cancers as well; click here for more)
Niacin Flush Management
Niacin-Hoffer Interview
Dr. Hoffer's Supplements
File Access
Reference Articles
External Links & References P2
Dietary-histone-deacetylases-HDACs-inhibitors-in-health-and-disease
Kynurenine-Pathway-Pathologies-CFS-FMS.2013
Here is a pathetic article from Harvard, 2019, that sites ancient articles and essentially says nothing:
Assessment of the Role of Niacin in Managing Cardiovascular Disease Outcomes.jama.2019